| 卡维地洛对原发性高血压患者血浆神经肽的影响 |
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| 引用本文： | 李倩,程光华,杨健.卡维地洛对原发性高血压患者血浆神经肽的影响[J].放射免疫学杂志,2008,21(5). |
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| 作者姓名： | 李倩 程光华 杨健 |
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| 作者单位： | 1. 皖南医学院弋矶山医院急诊内科,241001
2. 弋矶山医院核医学科 |
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| 摘 要： | 目的：为探讨卡维地洛对原发性高血压患者血浆神经肽Y（NPY）与神经降压肽（NT）水平的变化及其与高血压治疗的关系。方法：本文测定了56例原发性高血压患者用药前后血压、血浆NPY、NT的变化,30例健康人做为对照组。结果：原发性高血压组血浆NPY明显高于对照组（P〈0.01）;血浆NT低于对照组（P〈0.01）。卡维地洛治疗后血压明显下降;血浆NPY水平降低;NT水平升高。结论：卡维地洛对原发性高血压体内NPY、NT水平变化的影响,可能与其治疗作用有关。
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| 关 键 词： | 卡维地洛 原发性高血压 神经肽Y 神经降压肽 |
Effect of Carvedilol Treatment on Plasma Neuropeptides Levels in Patients with Essential Hypertension |
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| Li Qian,Cheng Guanhua,Yang Jian.Effect of Carvedilol Treatment on Plasma Neuropeptides Levels in Patients with Essential Hypertension[J].Journal of Radioimmanology,2008,21(5). |
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| Authors: | Li Qian Cheng Guanhua Yang Jian |
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| Abstract: | Objective To study the changes of plasma neuropeptide Y (NPY) and neurotension (NT) levels in patients with essential hypertension after treatment with carvedilol. Methods Blood pressure and plasma NPY and NT concentrations (with RIA) were measured in 56 patients with essential hypertension both before and after carvedilol therapy (5~10mg bid) for 3 months as well as 30 controls. Results Before treatment plasma NPY levels were significantly higher in hypertensive patients than those in controls (P<0.01), bu... |
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| Keywords: | carvedilol essential hypertension neuropeptide Y(NPY) neurotension(NT) |
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