自体血清(血浆)在基础医学研究中的应用

自体血清(血浆)因其富含广谱、齐全的基本营养成分和生物活性物质及对细胞生存、生长和生命活动具有调控或促进作用的细胞因子等,加上来源于自体的成分,因此,通常在应用上具备生物多样性、安全性、稳定性和相容性等特点和优势,使其在现代基础医学研究中的应用越来越广泛.为了进一步探究和更加科学地将自体血清(血浆)应用于体外细胞培养和组织工程研究中,本文通过对自体血清(血浆)的主要成分及基本生物学特性阐述自体血清(血浆)在细胞生物学和组织生物学研究中的应用.

Abstract：

Rich in a broad spectrum of basic nutritional ingredients and bioactive substances and cytokines which regulated or promoted the cell viability, cell growth and vital movement, autologous serum (plasma) embraced the characteristics of biological diversity, security, stability, compatibility and so on. These advantages helped the increasingly wide application of autologous serum (plasma) in modem preclinical medicine studies. To further explore the scientific application of autologous serum (plasma) in cell culture and tissue engineering in vitro, this paper analyzed the main components and basic bionomics of autologous serum (plasma), and explained its application in cytobiology and histology within the field of preclinical medicine. Literature review suggested that autologous serum played an active role in normal or abnormal cell culture in vitro, cell proliferation and differentiation, cell morphology, structure and metabolism, as well as the in vitro tissue culture, self- renewal, and self-repair. Moreover, the diversity of its biological characteristics and security justifed the application of autologous serum (plasma) in preclinical medicine studies.

Application of autologous serum (plasma) on preclinical medicine

Rich in a broad spectrum of basic nutritional ingredients and bioactive substances and cytokines which regulated or promoted the cell viability, cell growth and vital movement, autologous serum (plasma) embraced the characteristics of biological diversity, security, stability, compatibility and so on. These advantages helped the increasingly wide application of autologous serum (plasma) in modem preclinical medicine studies. To further explore the scientific application of autologous serum (plasma) in cell culture and tissue engineering in vitro, this paper analyzed the main components and basic bionomics of autologous serum (plasma), and explained its application in cytobiology and histology within the field of preclinical medicine. Literature review suggested that autologous serum played an active role in normal or abnormal cell culture in vitro, cell proliferation and differentiation, cell morphology, structure and metabolism, as well as the in vitro tissue culture, self- renewal, and self-repair. Moreover, the diversity of its biological characteristics and security justifed the application of autologous serum (plasma) in preclinical medicine studies.