| 噻托溴铵联合沙美特罗/丙酸氟替卡松治疗慢性阻塞性肺疾病稳定期患者的疗效观察 |
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| 引用本文： | 赵正宇,张爱观. 噻托溴铵联合沙美特罗/丙酸氟替卡松治疗慢性阻塞性肺疾病稳定期患者的疗效观察[J]. 国际呼吸杂志, 2011, 31(7): 490-492. DOI: 10.3760/cma.j.issn.1673-436X.2011.007.003 |
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| 作者姓名： | 赵正宇 张爱观 |
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| 作者单位： | 1. 平湖市第一人民医院呼吸科,314200
2. 平湖市中医院呼吸科,314200 |
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| 摘 要： | 目的 观察沙美特罗/丙酸氟替卡松(舒利迭)联合噻托溴铵粉吸入剂(思力华)对慢性阻塞性肺疾病(COPD)缓解期的治疗效果.方法 采用随机、双肓的方法将85例COPD患者分为观察组和对照组,观察组A组给予噻托溴铵和沙美特罗/丙酸氟替卡松治疗,对照组B组给予沙美特罗/内酸氟替卡松治疗.分别对两组患者治疗前后的呼吸困难的评分、...
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| 关 键 词： | 慢性阻塞性肺疾病 噻托溴铵 沙美特罗/丙酸氟替卡松 肺功能 |
Tiotropium bromide combined salmeterol/fluticasone propionate for the treatment in patients with stable chronic obstructive pulmonary disease |
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| ZHAO Zheng-yu,ZHANG Ai-guan. Tiotropium bromide combined salmeterol/fluticasone propionate for the treatment in patients with stable chronic obstructive pulmonary disease[J]. International Journal of Respiration, 2011, 31(7): 490-492. DOI: 10.3760/cma.j.issn.1673-436X.2011.007.003 |
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| Authors: | ZHAO Zheng-yu ZHANG Ai-guan |
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| Abstract: | Objective To evaluate the effects of tiotropium bromide combined salmeterol/fluticasone propionate (SFC) for the treatment in patients with stable chronic obstructive pulmonary disease(COPD). Methods A randomized, double blind clinical trial was conducted in 85 patients with stable COPD. Group A was given tiotropium bromide combined with SFC,Group B was given SFC,the St George's respiratory questionnaire (SGRQ), pulmonary function and 6 minute walk distance (6-MWD)was conducted at baseline, 3 monthes after treatment. Results FEV1 , FEV1/FVC%, SGRQ score and 6-MWD in combined group A were significantly superior to those of control group B at 3 monthes after treatment (all P ＜0.05). Conclusions Tiotropium bromide combined SFC could further advance efficacy than SFC for the treatment in patients with stable COPD. |
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| Keywords: | Chronic obstructive pulmonary disease Tiotropium bromide Salmeterol/fluticasone propionate Pulmonary function |
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