| 脾脏白髓结构特征以及维持其完整性的分子机制 |
| |
| 引用本文： | 王燕娟,曹建平. 脾脏白髓结构特征以及维持其完整性的分子机制[J]. 国际医学寄生虫病杂志, 2011, 38(2): 80-84. DOI: 10.3760/cma.j.issn.1673-4122.2011.02.004 |
| |
| 作者姓名： | 王燕娟 曹建平 |
| |
| 作者单位： | 中国疾病预防控制中心寄生虫病预防控制所,WHO疟疾、血吸虫病和丝虫病合作中心,卫生部寄生虫病原与媒介生物学重点实验室,上海,200025 |
| |
| 摘 要： | 脾脏是机体最大的外周免疫器官,白髓作为脾脏内淋巴细胞的聚集地,其结构的完整性包括T/B淋巴细胞区室化、清晰的边缘区、完整的滤泡树突状细胞网络及生发中心等特征,是机体对外来病原微生物作出快速且有效免疫应答的物质基础,深入探讨维持脾脏白髓结构完整性的分子机制将为相关疾病的防治提供理论支持.
|
| 关 键 词： | 脾脏 淋巴滤泡 生发中心 |
Features of the architecture in splenic white pulp and the molecular mechanisms for its integrity |
| |
| WANG Yan-juan,CAO Jian-ping. Features of the architecture in splenic white pulp and the molecular mechanisms for its integrity[J]. International JOurnal of Medical Parasitic Diseases, 2011, 38(2): 80-84. DOI: 10.3760/cma.j.issn.1673-4122.2011.02.004 |
| |
| Authors: | WANG Yan-juan CAO Jian-ping |
| |
| Abstract: | Spleen is the biggest peripheral immune organ. As the place where mature lymphocytes aggregated,the integrate architecture of splenic white pulp is the structural foundation for prompt and effective response of immune system. It includes distinct T/B segregation and marginal zone,existence of follicular dendritic cells network and germinal centers. Continuing researches on the mechanisms involved in the maintenance of the architecture in splenic white pulp will provide rationale for the prevention and treatment of the relating diseases. |
| |
| Keywords: | Spleen Lymphoid follicle Germinal center |
| 本文献已被 万方数据 等数据库收录！ |
