| 青春期女生尿液中大豆异黄酮代谢物与性发育的关系 |
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| 引用本文： | 章涵,赵玉霞. 青春期女生尿液中大豆异黄酮代谢物与性发育的关系[J]. 中国学校卫生, 2021, 42(7): 1080-1082. DOI: 10.16835/j.cnki.1000-9817.2021.07.028 |
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| 作者姓名： | 章涵 赵玉霞 |
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| 作者单位： | 信阳职业技术学院医学院, 河南 464000 |
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| 基金项目： | 河南省高等学校重点科研项目资助计划21A330005 |
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| 摘 要： | 目的 探讨尿液中大豆异黄酮代谢物与青春期女生性发育的关系,为女生青春期发育影响因素研究提供参考依据.方法 在信阳市1所小学随机选择符合纳入标准的50名五年级女生为研究对象,进行性发育评价及尿液中大豆异黄酮代谢物的测定.尿液中大豆异黄酮代谢物的测定运用超高速液相色谱-串联质谱分析法(UPLC-MS/MS).结果 不同性发...
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| 关 键 词： | 异黄酮类 青春期 性发育 生长和发育 学生 女(雌)性 |
| 收稿时间： | 2021-01-04 |
Relationship between soy isoflavone metabolites in urine and sexual development of adolescent girls |
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| Affiliation: | Medical School, Xinyang Vocational and Technical College, Xinyang (464000), Henan Province, China |
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| Abstract: | Objective To explore the relationship between urinary soybean isoflavone metabolites and sexual development of adolescent girls. Methods Fifty girls of grade 5 from one primary school in Xingang City who met the inclusion criteria were selected. Sexual characteristic development was assessed and soybean isoflavone metabolites in urine was tested by ultra-high speed liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Results Levels of dye xylinone in girls with different stages of sexual development (advanced, normal, and delayed groups) varied significantly (F=3.53, P < 0.05), highest in advanced group. Urinary genistein was significantly higher in menarche group than that of non-menarche group (t=2.16, P < 0.05). Urinary genistein may be associated with early sexual development among adolescent girls. Conclusion High level of urine genistein may be related to the early sexual development of adolescent girls. |
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