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人乳头瘤病毒疫苗临床应用中国专家共识
引用本文:中华医学会妇科肿瘤学分会,中国优生科学协会阴道镜和宫颈病理学分会. 人乳头瘤病毒疫苗临床应用中国专家共识[J]. 协和医学杂志, 2021, 12(2): 189-201. DOI: 10.12290/xhyxzz.2021-0082
作者姓名:中华医学会妇科肿瘤学分会  中国优生科学协会阴道镜和宫颈病理学分会
作者单位:1.华中科技大学同济医学院附属同济医院妇产科,武汉 430030
基金项目:国家自然科学基金重点项目81630060国家自然科学基金面上项目81974410妇幼健康研究会研究项目2018AMCHS008浙江省科技厅重点研发项目2020C03025上海市科学技术委员会科研计划项目18411963600
摘    要:人乳头瘤病毒(human papilloma virus,HPV)疫苗接种是预防HPV感染及相关疾病的有效方法,是防控HPV感染相关疾病的一级预防措施。低龄人群接种效果优于高龄人群,性暴露前接种免疫效果最佳。HPV疫苗不仅适用于普通人群,同样推荐用于高危、特殊人群。对于具有遗传易感、高危生活方式和HIV感染的适龄女性优先推荐接种HPV疫苗。适龄女性无论是否存在HPV感染、细胞学是否异常均可接种HPV疫苗。近期有妊娠计划、妊娠期或哺乳期女性不宜接种HPV疫苗。接种HPV疫苗后仍应进行子宫颈癌筛查。

关 键 词:人乳头瘤病毒   疫苗   临床应用   高危   特殊人群
收稿时间:2021-01-22

Chinese Expert Consensus on Clinical Application of Human Papilloma Virus Vaccine
Affiliation:1.Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China2.Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China3.Women's Hopital, School of Medicine Zhejiang University, Hangzhou 310006, China, E-mail: xiex@ zju.edu.cn4.Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China
Abstract:Human papilloma virus (HPV) vaccination is a primary preventive measure and an effective method to prevent HPV infection and the related diseases. Its effect in young women is better, and the immune efficacy of vaccination for teenagers before sexual exposure is the best. HPV vaccine is not only suitable for the general population, but also recommended for high-risk and special groups. HPV vaccination should be recommended for women at the appropriate age with genetic susceptibility, high-risk lifestyle, or HIV infection. No matter whether they have HPV infection or abnormal cytology, women of appropriate ages can be vaccinated. Women with a pregnancy plan in the near future and pregnant or lactating women should not be vaccinated. Recommendation of cervical cancer screening should be carried out after HPV vaccination.
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