国产奈达铂致严重过敏反应8例报道

目的探讨国产奈达铂联合或单药化疗过程中出现奈达铂致严重过敏反应患者的抢救和护理。方法回顾性分析2011年1月至2014年7月我科收治的肿瘤患者在使用奈达铂化疗过程中8例发生严重过敏反应的患者救治及护理。结果经医护人员及时发现与抢救,8例发生严重过敏反应的患者症状缓解,生命体征均恢复正常。结论奈达铂应用过程中易出现过敏反应,用药过程加强巡视,密切观察患者用药后的反应,及早发现,及时处理。

Clinical Observation of Eight Cases with Severe Allergic Reaction Treated with Domestic Nedaplatin

Objective To investigate rescue and nursing of patients with severe allergic reaction induced by nedaplatin treated with domestic nedaplatin combination or single agent chemotherapy. Methods 73 patients emerging adverse events during treatment with nedaplatin chemotherapy was enrolled duling January 2011 to July 2014 at our department. Of which eight patient received rescue and nursing due to severe allergic reaction were summarized and analyzed. Results Eight patient with severe allergic reaction were all relief and recovered after timely rescuing and nursing. Conclusion Nedaplatin chemotherapy was widly used in clinical practice. It is worthy to inquire allergic history of patient and necessary to educate to patient because of high incidence of a, Uergic reaction. Inspection to patient during treatment with nedaplatin chemotherapy should be strengthened. Close observation should be given to patient after received nedaplatin in order to avoid risk and ensure patients＇ safety.