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依达拉奉联合纳洛酮治疗DEACMP的疗效观察
引用本文:龙海丽.依达拉奉联合纳洛酮治疗DEACMP的疗效观察[J].西部医学,2011,23(5):912-913,915.
作者姓名:龙海丽
作者单位:云梦县人民医院内二科,湖北云梦,432500
摘    要:目的探讨依达拉奉联合纳洛酮治疗急性一氧化碳中毒迟发性脑病(DEACMP)的临床疗效。方法 68例DEACMP患者随机分为联合治疗组及对照组各34例。联合治疗组在常规治疗基础上加用依达拉奉30 mg/次,2次/d静滴,纳洛酮注射液2 mg/次,1次/d,静滴;对照组在常规治疗基础上加用纳洛酮注射液2 mg/次,1次/d,静滴,疗程均为15 d。治疗后评价各组临床疗效。结果联合治疗组总有效率91.2%,对照组总有效率73.5%,两组疗效比较差异有显著性(P〈0.05);联合治疗组治疗后HDS评分明显高于对照组(P〈0.05),P300潜伏期明显缩短(P〈0.05)。结论依达拉奉联合纳洛酮治疗一氧化碳中毒迟发性脑病疗效良好,值得临床推广。

关 键 词:一氧化碳中毒  迟发性脑病  依达拉奉  纳洛酮

Observation of the curative effect of edaravone combined with naloxone in treating delayed encephalopathy after acute carbon monoxide poisoning
LONG Hai-li.Observation of the curative effect of edaravone combined with naloxone in treating delayed encephalopathy after acute carbon monoxide poisoning[J].Medical Journal of West China,2011,23(5):912-913,915.
Authors:LONG Hai-li
Institution:LONG Hai-li(Depantment of The Second Internal Medicine,The People's Hospital of Yunmeng,Yunmeng 432500,Hubei)
Abstract:Objective To research the clinical curative effect of edaravone combined with naloxone on treatment of the delayed encephalopathy after acute carbon monoxide poisoning.Methods 68 cases of DEACMP were randomly divided into combined treatment group(34 cases) and control group(34 cases).Based on the basic treatments,combined treatment group was treated with edaravone(30mg,bid) and naloxone(2 mg,qd) and control group was treated with naloxone(2 mg,qd).The course of treatment was 15 days.The clinical effect of t...
Keywords:Carbon monoxide poisoning  Delayed encephalopathy  Edaravone  Naloxone  
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