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肝癌根治术后肝内复发合并肝外转移积极手术治疗10例
引用本文:刘煌,陈达丰,李冉冉,陈文有,柯恩明,张文华,刘静.肝癌根治术后肝内复发合并肝外转移积极手术治疗10例[J].世界华人消化杂志,2011(27).
作者姓名:刘煌  陈达丰  李冉冉  陈文有  柯恩明  张文华  刘静
作者单位:中国人民解放军第一七五医院(厦门大学附属东南医院)普外科;
摘    要:目的:探讨对严格选择的肝癌根治术后肝内复发并肝外转移患者采取积极外科治疗策略的临床价值.方法:回顾性分析10例肝癌根治术后肝内复发伴肝外孤立转移灶病例的外科治疗情况.并与行保守治疗的肝癌根治术后肝内复发伴肝外转移的48例患者的生存情况进行比较.结果:Kaplan-Meier生存分析显示积极外科治疗组复发后中位生存时间为45.0mo±5.1mo,保守治疗组复发后中位生存时间仅为12.0mo±2.1mo.Log-rank检验对两组生存时间比较,发现积极手术治疗组生存时间显著长于保守治疗组(P<0.01)结论:对于严格选择的病例采取肝外孤立转移灶切除联合肝内复发灶切除或局部治疗的积极外科治疗策略能够显著提高患者生存时间.

关 键 词:肝细胞癌  复发  手术治疗  

Aggressive management of patients with extrahepatic and intrahepatic recurrences of hepatocellular carcinoma: an analysis of 10 cases
Huang Liu,Da-Feng Chen,Ran-Ran Li,Wen-You Chen,En-Ming Ke,Wen-Hua Zhang,Jing Liu.Aggressive management of patients with extrahepatic and intrahepatic recurrences of hepatocellular carcinoma: an analysis of 10 cases[J].World Chinese Journal of Digestology,2011(27).
Authors:Huang Liu  Da-Feng Chen  Ran-Ran Li  Wen-You Chen  En-Ming Ke  Wen-Hua Zhang  Jing Liu
Institution:Huang Liu,Da-Feng Chen,Ran-Ran Li,Wen-You Chen,En-Ming Ke,Wen-Hua Zhang,Jing Liu,Department of General Surgery,the 175th Hospital of Chinese PLA (Southeast Hospital Affiliated to Xiamen University),Zhangzhou 363000,Fujian Province,China
Abstract:AIM: To evaluate the value of combined resection and locoregional therapy in the management of selected patients with extrahepatic and intrahepatic recurrences of hepatocellular carcinoma. METHODS: The clinical data for 10 patients with extrahepatic and intrahepatic recurrences of hepatocellular carcinoma who underwent resection of extrahepatic recurrence and reresection or locoregional therapy for intrahepatic recurrence were analyzed retrospectively. The survival of these 10 patients was compared with oth...
Keywords:Hepatocellular carcinoma  Recurrence  Surgical therapy  
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