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丙型肝炎病毒感染相关睡眠障碍的研究进展
引用本文:孙晓琦,方南元,张征波,薛博瑜. 丙型肝炎病毒感染相关睡眠障碍的研究进展[J]. 世界华人消化杂志, 2011, 0(36)
作者姓名:孙晓琦  方南元  张征波  薛博瑜
作者单位:南京中医药大学第一临床医学院;
基金项目:艾滋病和病毒性肝炎等重大传染病防治国家科技重大专项“慢性丙型肝炎证候规律及中西医结合治疗方案研究”,No.2008ZX10005-009
摘    要:据WHO的统计,全球约有1.71亿人罹受丙型肝炎病毒(hepatitis C virus,HCV)的感染[1].伴随HCV的感染,患者常常会出现疲劳、睡眠障碍、抑郁等身心异常的状态.既往有文献报道丙肝患者存在睡眠的问题,但往往淹没在众多肝纤维化及终末期肝病相关的睡眠障碍文献中,鲜有人关注与HCV感染直接相关的睡眠障碍[2].近年来,有少量的文献致力于慢性丙型肝炎睡眠障碍的探讨,让人惊讶的是睡眠问题在慢性丙肝患者中存在着很大程度的普遍性,有证据提示其可能独立于干扰素的治疗.对HCV感染相关睡眠障碍的研究可能会为慢性丙型肝炎的发生、发展及转归提供新的研究思路,也有利于提高患者生活质量,优化现有的治疗方案.

关 键 词:丙型肝炎病毒  慢性丙型肝炎  睡眠障碍  

Advances in research of sleep disturbance in patients with hepatitis C virus infection
Xiao-Qi Sun,Nan-Yuan Fang,Zheng-Bo Zhang,Bo-Yu Xue,the First Clinical Medical College,Nanjing University of Chinese Medicine,Nanjing ,Jiangsu Province,China. Advances in research of sleep disturbance in patients with hepatitis C virus infection[J]. World Chinese Journal of Digestology, 2011, 0(36)
Authors:Xiao-Qi Sun  Nan-Yuan Fang  Zheng-Bo Zhang  Bo-Yu Xue  the First Clinical Medical College  Nanjing University of Chinese Medicine  Nanjing   Jiangsu Province  China
Affiliation:Xiao-Qi Sun,Nan-Yuan Fang,Zheng-Bo Zhang,Bo-Yu Xue,the First Clinical Medical College,Nanjing University of Chinese Medicine,Nanjing 210000,Jiangsu Province,China
Abstract:According to the WHO statistics,approximately 171 million people are infected by hepatitis C virus (HCV) worldwide.Chronic HCV infection is associated with physical and mental symptoms including fatigue,sleep disturbance,and depression that adversely affect quality of life.But sleep disturbance has received little attention in the literature,with the exception of sleep changes noted in patients with cirrhosis and end-stage liver disease.More studies focusing on the role of chronic hepatitis C (CHC) infectio...
Keywords:Hepatitis C virus  Chronic hepatitis C  Sleep disorders  
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