| microRNA与大肠癌关系的研究进展 |
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| 引用本文： | 王炎,宋贯霞,李琦.microRNA与大肠癌关系的研究进展[J].世界华人消化杂志,2011(33). |
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| 作者姓名： | 王炎 宋贯霞 李琦 |
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| 作者单位： | 上海中医药大学附属普陀医院中西医结合肿瘤介入研究所;上海中医药大学附属普陀医院超声科; |
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| 基金项目： | 上海市自然基金资助项目,No.09ZR1428500; 上海市教委创新行动重点基金资助项目,No.12ZZ118; 上海市重点学科基金资助项目,No.S30302 |
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| 摘 要： | 大肠癌的发病是一个多因素、多步骤的演进过程,基因表达异常在其中起重要作用.近年来研究证实microRNA(miRNA,微小核糖核酸)广泛存在于真核生物体内,与大肠癌相关基因表达调控密切相关.这些发现极大地扩展了大肠癌的发病机制,为大肠癌的诊断和分子靶向治疗提供了新的思路和手段.
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| 关 键 词： | 大肠癌 microRNAs 机制 表达 |
Advances in understanding the relationship between microRNAs and colorectal cancer |
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| Yan Wang,Qi Li.Advances in understanding the relationship between microRNAs and colorectal cancer[J].World Chinese Journal of Digestology,2011(33). |
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| Authors: | Yan Wang Qi Li |
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| Institution: | Yan Wang,Qi Li,Department of Oncology,the Affi liated Putuo Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China Guan-Xia Song,Department of Ultrasonography,the Aff iliated Putuo Hospital of Shanghai University of Traditional Chinese Medicine,China |
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| Abstract: | The development of colorectal cancer is a multifactorial, multi-step process in which abnormal gene expression may play an important role. In recent years, it has been reported that microRNAs (miRNAs), which widely exist in eukaryotes, are closely related to gene expression regulation in colorectal cancer. These findings have greatly expanded our understanding of the pathogenesis of colorectal cancer and provide new ideas and methods for the diagnosis and treatment of this malignancy. |
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| Keywords: | Colorectal cancer MicroRNAs Mechanism Expression |
| 本文献已被 CNKI 等数据库收录！ |
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