| 肿瘤抗淋巴管生成研究进展 |
| |
| 引用本文： | 吴而回,燕敏.肿瘤抗淋巴管生成研究进展[J].世界华人消化杂志,2011(24):2555-2561. |
| |
| 作者姓名： | 吴而回 燕敏 |
| |
| 作者单位： | 上海交通大学医学院附属瑞金医院普外科; |
| |
| 摘 要： | 肿瘤转移是癌症患者的主要死因之一,淋巴管转移是肿瘤转移的重要途径,研究发现VEGF-C/VEGF-D/VEGFR-3与肿瘤淋巴管生成、肿瘤转移、肿瘤预后密切相关.大量的研究证实VEGF-C/VEGF-D/VEGFR-3信号传导轴在调节肿瘤淋巴管生成中起主导作用,临床病理研究也显示VEGF-C/VEGF-D/VEGFR-...
|
| 关 键 词： | 淋巴管 血管内皮生长因子 分子生物学 |
Lymphangiogenesis in cancers:a therapy target |
| |
| Er-Hui Wu,Min Yan.Lymphangiogenesis in cancers:a therapy target[J].World Chinese Journal of Digestology,2011(24):2555-2561. |
| |
| Authors: | Er-Hui Wu Min Yan |
| |
| Institution: | Er-Hui Wu,Min Yan,Department of General Surgery,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China |
| |
| Abstract: | Tumor metastasis is a major cause of death among cancer patients.The lymphatic vasculature is an important route for the metastatic spread of cancer.Recent research has indicated that vascular endothelial growth factor C(VEGF-C),VEGF-D and VEGF receptor-3(VEGFR-3) are closely related to tumor-induced lymphangiogenesis,tumor metastasis and prognosis.Numerous studies demonstrate that the VEGF-C/VEGF-D/VEGFR-3 signaling axis plays a leading role in the regulation of tumor lymphangiogenesis and is related to tu... |
| |
| Keywords: | Lymphatic vasculature Vascular endothelial growth factor Molecular biology |
| 本文献已被 CNKI 等数据库收录！ |
|
