| 人工肝结合~(131)I治疗与内科常规治疗40例甲亢合并重症肝损害疗效的比较 |
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| 引用本文： | 杨丽霞,李小鹏,张伦理. 人工肝结合~(131)I治疗与内科常规治疗40例甲亢合并重症肝损害疗效的比较[J]. 世界华人消化杂志, 2011, 0(28) |
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| 作者姓名： | 杨丽霞 李小鹏 张伦理 |
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| 作者单位： | 南昌大学第一附属医院传染科; |
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| 摘 要： | 目的:对人工肝结合131I治疗与内科常规治疗甲状腺功能亢进(甲亢)合并重症肝损害患者的临床疗效进行比较.方法:对近6年来我院40例甲亢合并重症肝损害患者的临床表现、实验室检查、治疗方式及预后进行回顾性分析,比较采用人工肝[方式有分子吸附再循环系统(molecula radsorbent recirculating system,MARS)、血浆置换]结合131I与内科常规治疗的疗效和预后.结果:人工肝组有25例患者,20例好转,5例病情恶化,内科常规治疗组共15例患者,6例好转,9例恶化,人工肝组好转率(80%)明显高于内科常规治疗组(40%),人工肝治疗能显著改善患者肝功能、甲状腺功能指标,缩短凝血酶原时间,提高治愈率.结论:甲亢合并重症肝损害病情复杂,治疗棘手,根据病情需要行人工肝治疗,在肝功能改善后行131I能明显改善预后,提高生存率,降低病死率.
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| 关 键 词： | 肝 人工 131I治疗 甲状腺功能亢进 重型肝炎 |
Clinical effect of artif icial livercombined with 131I therapy versus conventional medical treatment in patients with hyperthyroidism and severe liver injury:an analysis of 40 cases |
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| Li-Xia Yang,Xiao-Peng Li,Lun-Li Zhang. Clinical effect of artif icial livercombined with 131I therapy versus conventional medical treatment in patients with hyperthyroidism and severe liver injury:an analysis of 40 cases[J]. World Chinese Journal of Digestology, 2011, 0(28) |
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| Authors: | Li-Xia Yang Xiao-Peng Li Lun-Li Zhang |
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| Affiliation: | Li-Xia Yang,Xiao-Peng Li,Lun-Li Zhang,Department of Infectious Diseases,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China |
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| Abstract: | AIM:To evaluate the clinical effect of artificialliver combined with 131I therapy versus conventional medical treatment in patients with hyperthyroidism and severe liver injury.METHODS:The clinical data for 40 patientswith hyperthyroidism and severe liver injurywho were treated at our hospital over the past 6years were retrospectively analyzed to comparethe efficacy of artificial liver combined with 131Itherapy versus conventional medical treatment.RESULTS:Twenty-five patients underwentartificial liver trea... |
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| Keywords: | Artificial liver 131I therapy Hyperthyroidism Severe hepatitis |
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