| 5-HT及电刺激对胃节律紊乱模型新西兰白兔胃电活动的影响 |
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| 引用本文： | 黄伟锋,张慧,欧阳守,卢春敬. 5-HT及电刺激对胃节律紊乱模型新西兰白兔胃电活动的影响[J]. 世界华人消化杂志, 2011, 0(23): 2486-2491 |
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| 作者姓名： | 黄伟锋 张慧 欧阳守 卢春敬 |
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| 作者单位： | 厦门市医药研究所生理室;厦门市妇幼保健院输血科; |
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| 基金项目： | 福建省科技厅重点基金资助项目,No.2009D026; 福建省卫生厅青年科研课题基金资助项目,No.2009-2-89,No.2010-2-112~~ |
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| 摘 要： | 目的:观察5-HT及电刺激对胃节律紊乱模型新西兰白兔胃电活动的影响.方法:对以胰高血糖素造模的新西兰白兔胃节律紊乱模型采用外周注射5-HT、胃起步点起搏,电刺激室旁核和中缝大核(P7)的方法,四导胃浆膜电信号同步记录,分析胃体、及胃窦部胃电信号的平均频率,相位差,负相位比率,波形对应率,幅度等指标,考察5-HT,及电刺...
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| 关 键 词： | 胃节律紊乱 五羟色胺 电刺激 浆膜胃电活动 新西兰白兔 |
Effect of 5-HT and electrical stimulating on gastric electric activity in rabbits with gastric dysrhythmia |
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| Wei-Feng Huang,Hui Zhang,Shou Ouyang,Xiamen Medical Research Institute,Xiamen ,Fujian Province,China Chun-Jing Lu,Xiamen Maternity , Child Health Care Hospital,Xiamen ,China. Effect of 5-HT and electrical stimulating on gastric electric activity in rabbits with gastric dysrhythmia[J]. World Chinese Journal of Digestology, 2011, 0(23): 2486-2491 |
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| Authors: | Wei-Feng Huang Hui Zhang Shou Ouyang Xiamen Medical Research Institute Xiamen Fujian Province China Chun-Jing Lu Xiamen Maternity Child Health Care Hospital Xiamen China |
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| Affiliation: | Wei-Feng Huang,Hui Zhang,Shou Ouyang,Xiamen Medical Research Institute,Xiamen 361008,Fujian Province,China Chun-Jing Lu,Xiamen Maternity and Child Health Care Hospital,Xiamen 361003,China |
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| Abstract: | AIM:To evaluate the effect of 5-hydroxytryptamine(5-HT) and electrical stimulation on gastric electric activity(GEA) in rabbits with gastric dysrhythmia(GD).METHODS:GD was induced in rabbits by peripheral injection of glucagon.Peripheral injection of 5-HT,gastric pacemaking,and electrical stimulation of the paraventricular nucleus(PVN) and raphe magnus(RM,P7) were performed in GD rabbits.Four pairs of bipolar Ag-AgCl elec-trodes implanted on the serosa along the gastric greater curve were used for recording... |
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| Keywords: | Gastric dysrhythmia 5-HT Electrical stimulation Gastric electric activity Rabbit |
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