| 胰腺癌切除术后辅助放化疗治疗疗效的Meta分析 |
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| 引用本文： | 王思亮,林艳,高嵩,胡天玉,吴荣.胰腺癌切除术后辅助放化疗治疗疗效的Meta分析[J].世界华人消化杂志,2011(31). |
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| 作者姓名： | 王思亮 林艳 高嵩 胡天玉 吴荣 |
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| 作者单位： | 中国医科大学附属盛京医院第二肿瘤科;中国医科大学附属盛京医院第二消化内科; |
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| 摘 要： | 目的:通过Meta分析探讨辅助放化疗在胰腺癌术后患者治疗中的意义.方法:计算机检索Pubmed(1970/2011-07)、EMbase(1974/2011-07)、Cochrane图书馆(2011年第7期)、中国生物医学文献数据库(1978/2011-07)、ASCO等论文集检索相关发表及未发表的文献,查找有关胰腺癌术后辅助放化疗的临床试验研究.由2名评价者独立选择试验、提取资料和评估方法学质量,而后采用Cochrane协作网RevMan5.0软件进行统计分析.对辅助治疗组和观察组2年生存率、5年生存率进行Meta分析.结果:8个随机对照临床试验共1507例患者纳入分析,放化疗联合治疗组与观察组比较,2年生存率比较,生存优势为OR=1.96,95%CI(1.55,2.48),结果具有统计学意义;5年生存率比较,生存优势为OR=1.89,95%CI(1.41,2.53),结果具有统计学意义.结论:现有证据支持胰腺癌术后进行辅助放化疗可提高生存率.
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| 关 键 词： | 胰腺癌 辅助治疗 Meta分析 |
Efficacy of adjuvant chemoradiotherapy in pancreatic cancer patients after surgical resection:a meta-analysis |
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| Si-Liang Wang,Yan Lin,Song Gao,Tian-Yu Hu,Rong Wu.Efficacy of adjuvant chemoradiotherapy in pancreatic cancer patients after surgical resection:a meta-analysis[J].World Chinese Journal of Digestology,2011(31). |
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| Authors: | Si-Liang Wang Yan Lin Song Gao Tian-Yu Hu Rong Wu |
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| Institution: | Si-Liang Wang,Yan Lin,Song Gao,Tian-Yu Hu,Rong Wu,Department of Medical Oncology & Department of Gastroenterology,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning Province,China |
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| Abstract: | AIM:To conduct a meta-analysis to evaluate the efficacy of adjuvant chemoradiotherapy in pancreatic cancer patients after surgical resection.METHODS:PubMed(1970/2011-07) ,EMbase(1974/2011-07) ,the Cochrane Library(Issue 7,2011) ,CBM(1978/2011-07) and ASCO were searched to retrieve relevant published and unpublished studies evaluating the efficacy of adjuvant chemoradio-therapy in pancreatic cancer patients after surgical resection.A meta-analysis of the overall survival(OS) data from randomized controlled t... |
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| Keywords: | Pancreatic cancer Adjuvant therapy Meta-analysis |
| 本文献已被 CNKI 等数据库收录！ |
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