| 五羟色胺与慢性便秘 |
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| 引用本文： | 张卫平,江滨. 五羟色胺与慢性便秘[J]. 世界华人消化杂志, 2011, 0(24): 2551-2554 |
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| 作者姓名： | 张卫平 江滨 |
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| 作者单位： | 南京中医药大学;南京市中医院全国中医肛肠医疗中心; |
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| 摘 要： | 五羟色胺(5-hydroxytryptamine,5-HT)是肠神经系统中一重要的单胺类神经递质.95％来源于消化系统,其中90％位于肠黏膜的嗜铬细胞(enterochromaffin cells,EC),10％位于肠道神经元.5-HT在引发胃肠蠕动和分泌反射,以及调节内脏感觉中起关键作用.有关5-HT在功能性胃肠疾病...
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| 关 键 词： | 5羟色胺 慢性便秘 5羟色胺受体 |
Role of serotonin in the pathogenesis of chronic constipation |
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| Wei-Ping Zhang,Nanjing University of Chinese Medicine,Nanjing ,Jiangsu Province,China Bin Jiang,National Medical Center for Colorectal Disease,Nanjing Hospital of Traditional Chinese Medicine,China. Role of serotonin in the pathogenesis of chronic constipation[J]. World Chinese Journal of Digestology, 2011, 0(24): 2551-2554 |
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| Authors: | Wei-Ping Zhang Nanjing University of Chinese Medicine Nanjing Jiangsu Province China Bin Jiang National Medical Center for Colorectal Disease Nanjing Hospital of Traditional Chinese Medicine China |
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| Affiliation: | Wei-Ping Zhang,Nanjing University of Chinese Medicine,Nanjing 210000,Jiangsu Province,China Bin Jiang,National Medical Center for Colorectal Disease,Nanjing Hospital of Traditional Chinese Medicine,China |
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| Abstract: | Serotonin(5-hydroxytryptamine,5-HT) is a monoamine neurotransmitter of profound importance in the enteric nervous system.About 95% of the serotonin in the body is found in the GI tract;90% is in enterochromaffin cells(EC cells) and the remaining 10% in enteric neurons.It plays a key role in the initiation of peristaltic and secretory reflexes and in the modulation of visceral sensations.There are many reports of serotonin in functional bowel disorders,and most of them mainly focus on irritable bowel syndrom... |
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| Keywords: | Serotonin Chronic constipation 5-HT receptors |
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