| 血必净对大鼠重症急性胰腺炎的治疗作用 |
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| 引用本文： | 耿小峰,脱红芳,彭彦辉,赵宝川.血必净对大鼠重症急性胰腺炎的治疗作用[J].世界华人消化杂志,2011(24):2567-2571. |
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| 作者姓名： | 耿小峰 脱红芳 彭彦辉 赵宝川 |
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| 作者单位： | 河北省人民医院普外科; |
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| 基金项目： | 河北省中医药管理局资助项目,No.2009047~~ |
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| 摘 要： | 目的:探讨血必净对大鼠重症胰腺炎(severe acute pancreatitis,SAP)的治疗作用.方法:经十二指肠乳头逆行胆胰管注射3.5％牛磺胆酸钠建立SAP模型,给予血必净治疗,观察血清中淀粉酶含量、白介素-6(interleukin-6,IL-6)、丙二醛(malondialdehyde,MDA)、超氧化...
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| 关 键 词： | 血必净 白介素-6 内毒素 丙二醛 超氧化物歧化酶 重症急性胰腺炎 |
Therapeutic effect of Xuebijing on experimental severe acute pancreatitis in rats |
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| Xiao-Feng Geng,Hong-Fang Tuo,Yan-Hui Peng,BaoChuan Zhao.Therapeutic effect of Xuebijing on experimental severe acute pancreatitis in rats[J].World Chinese Journal of Digestology,2011(24):2567-2571. |
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| Authors: | Xiao-Feng Geng Hong-Fang Tuo Yan-Hui Peng BaoChuan Zhao |
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| Institution: | Xiao-Feng Geng,Hong-Fang Tuo,Yan-Hui Peng,BaoChuan Zhao,Department of General Surgery,Hebei General Hospital,Shijiazhuang 050051,Hebei Province,China |
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| Abstract: | AIM:To study the therapeutic effect of Xuebijing on pancreatic injury in rats with experimental severe acute pancreatitis(SAP).METHODS:SAP was induced in rats by retrograde injection of 3.5% sodium taurocholate into the biliopancreatic duct.Xuebijing was then intraperitoneally injected in SAP rats.The levels of serum amylase,interleukin-6(IL-6),malondialdehyde(MDA),superoxide dimutase(SOD),and lipopolysaccharide(LPS) were measured,and pancreatic pathological changes were evaluated.RESULTS:Compared to normal... |
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| Keywords: | Xuebijing Interleukin-6 Lipopolysaccharide Malondialdehyde Superoxide dimutase Severe acute pancreatitis |
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