CT引导下经皮肺穿刺活检120例临床报告

目的探讨CT引导下经皮肺穿刺活检术的临床应用价值和安全性。方法经CT扫描判断病变部位选择最佳位置,采用美国巴德公司生产的穿刺针活检,所获得标本做常规病理、免疫组织化学,肺腺癌标本做基因突变分析。结果本组120例,行肺穿刺141次,21例做过2次;孤立性病变82例,确诊为肺癌58例,良性病变24例。弥漫性病变38例,确诊为肺癌27例,良性病变11例。9例肺腺癌标本测定基因突变,阳性结果5例。气胸13例(10.83%),少量咯血30例,胸痛5例,术后晕厥1例。结论 CT引导下肺穿刺活检术具有定位准确、安全可靠、穿刺成功率和定性判断准确率高,并发症少的特点,对肺部病变的诊断具有重要价值。基因突变分析为肺腺癌治疗的理想选择提供可靠依据。

Percutaneous CT-guided fine-needle aspiration of pulmonary lesions: the clinical results of 120 cases

Objective To evaluate the efficiency and safety of CT-guided percutaneous fine-needle aspiration of pulmonary le- sions. Methods The excellence sites were selected by CT, and lung biopsy was done. The specimens were examined simuhaneusly rou- tine pathology and immunohistory chemistry. The gene mutational analysis was done in the lung adenocarcinoma. Results 141 biopsies were done in 120 cases ,2 biopsies were done in 21 cases. Fifty-eight of cases lung cancer were diagnosed in 82 nodule isolations ,24 ca- ses were benign lesions. 27 cases of lung cancers were diagnosed in 38 diffuse lesions, 11 cases were benign lesions. The gene mutation- al analysis was examined in 9 lung adenocarcinomas. The results were positive in 5 cases. Phneumothoraxwas in 13 cases （ 10.83% ）, hemoptysis in 30 cases, chest pain in 5 cases,syncope in 1 case after biopsy. Conclusion The percutaneous CT-guided fine-needle as- piration of pulmonary lesions was an effective and safe procedure. The diagnostic accuracy is high. The complications are low. The gene mutational analysis is an importance basis to therapy of lung adenocarcinoma.