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Cubic Iron Core–Shell Nanoparticles Functionalized to Obtain High-Performance MRI Contrast Agents
Authors:Maria Volokhova,Anna Shugai,Masahiko Tsujimoto,Anna-Liisa Kubo,Sven Telliskivi,Mait Nigul,Peep Uudekü  ll,Heiki Vija,Olesja M. Bondarenko,Jasper Adamson,Anne Kahru,Raivo Stern,Liis Seinberg
Abstract:Nanoparticles with SiO 2 coating were synthesized to have a cubic iron core. These were found to have saturation magnetization very close to the highest possible value of any iron-containing nanoparticles and the bulk iron saturation magnetization. The in vitro toxicology studies show that they are highly biocompatible and possess better MRI contrast agent potential than iron oxide NPs.
Keywords:nanomaterials   synthesis   magnetic properties   MRI contrast agents   toxicity   ROS
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