肝硬化患者胃粘膜幽门螺杆菌检出的初步观察

本文对72例肝硬化患者进行了胃镜下胃粘膜活检检测幽门螺杆菌（HP）。组织学检查HP阳性42例，阳性率58．33％，HP感染和患者的肝功能Child分级无明显相关，亦和胃镜下食管静脉曲张的有无及曲张的严重程度无显著相关，而和胃粘膜活动性炎症及二十指肠溃疡的发生有明显相关。认为在肝硬化患者中，所存在的慢性活动性胃炎的主要病因仍是HP感染，HP可能在肝源性十二指肠溃疡的发病机制中起重要作用。

Preliminary Studies on Helicobacter Pylori in Gastric Mucosa or Patients with Liver Cirrhosis

In this paper, helicobacter pylori(HP) in gastric mucosa, which were obtained with the endoscopy procedure, were detected by histologic techniques in 72 patients whih liver cirrhosis. HP positive rate was 58.33%. HP infection was not related to the Child grades and esophageal varices degrees. A positive correlation was noted between HP infection and incidences of active gastritis and duodenal ulcer. We conclude that the HP infection is main cause of the chronic active gastritis and may play an important role on the pathogenesis of the hepatogenous duodenal ulcer in patients with liver cirrhosis.