微量元素硒与萎缩性胃炎关系的研究

为研究萎缩性胃炎及肠上皮化生与胃癌的关系，我们对42例胃癌，38例萎缩性胃炎和38例浅表性胃炎的血浆，尿液和胃液中Se含量进行了检测。结果提示：（1）萎缩性胃炎与胃癌的关系密切，特别是重度萎缩性胃炎和伴肠化者与胃癌尤为密切，应严密观察和随访行病理检查，对胃部的早期发现有一定帮助。（2）随胃炎加重，Se含量炎加重，Se含量呈阶梯状变化，对临床治疗和防止胃炎进一步发展有一定的指导意义；（3）适量补硒在胃癌防治上具有一定意义。

Study of Relationship Between Trace Element Selenium and Chronic Atrophic Gastritis

In order to study relationship between chronic atrophic gastritis and gastric carcinoma,the selenium levels in plasma,urine and gastric juice were determined in 42 cases of gastric carcinoma, 38 cases of chronic atrophic gastritis and 39 cases of chronic superficial gastritis. The result showed: (1) the chronic atrophic gastritis, especially severe types and with intestinal metaplasia,was closely bound up with gastric carcinoma. At the clinic,tightobservation,follow-up and biopsy to chronic atrophic gastritis played a certain role in early stage diagnosis of gastic carcinoma; (2)content of trace element selenium took place chang by degrees in pace with development of chronic gastritis. Determination of selenium had certainly directive function in treatment and avosiding development of chronic gastritis;(3)suitable selenium replenised had important significance in prevention and treatment of gastric carcinoma.