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Effects of Medicinal Cake-Separated Moxibustion on Plasma 6-Keto-PGF1α and TXB2 Contents in the Rabbit of Hyperlipemia
引用本文:常小荣,严洁,岳增辉,沈菁,林亚平,易受乡,曹湘平,王友京. Effects of Medicinal Cake-Separated Moxibustion on Plasma 6-Keto-PGF1α and TXB2 Contents in the Rabbit of Hyperlipemia[J]. 中医杂志(英文版), 2005, 25(2): 145-147
作者姓名:常小荣  严洁  岳增辉  沈菁  林亚平  易受乡  曹湘平  王友京
作者单位:Department of Acupuncture & Massage Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China,Department of Acupuncture & Massage,Hunan College of TCM,Changsha 410007,China
摘    要:Hyperlipemia rabbit models established with high cholesterol and fat diet were treated vith directmoxibustion and medicinal cake-separated moxibustion. The post-treatment plasma 6-keto-prostaglandin F_(1α)(6-keto-PGF_(1α)) and thromboxane B2 (TXB_2) contents were determined by radioimmunoassay. Resultsindicated that the plasma 6-keto-PGF_(1α) content significantly increased,the TXB_2 level decreased (P<0.05)and the TXB_2 /6-keto-PGF_(1α) ratio also decreased (P<0.01) in the medicinal cake-separated moxibustiongroup as compared with those in the model group respectively,but there was no significant differencebetween the medicinal cake-separated moxibustion group and the direct moxibustion group (P>0.05),suggesting that both the medicinal cake-separated moxibustion and direct moxibustion can regulate theplasma 6-keto-PGF_(1α) and TXB_2 contents,and the TXB_2/6-keto-PGF_(1α) ratio with similar actions,and have acertain protective action on endothelial cells of the aorta in the rabbit of hyperlipemia

关 键 词:6-Keto-PGF1α TXB2 高血脂 兔 动物实验 中医药疗法 山楂 大黄 中药汤剂

Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia.
Chang Xiaorong,Yan Jie,Yue Zenghui,Shen Jing,Lin Yaping,Yi Shouxiang,Cao Xiangping. Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia.[J]. Journal of Traditional Chinese Medicine, 2005, 25(2): 145-147
Authors:Chang Xiaorong  Yan Jie  Yue Zenghui  Shen Jing  Lin Yaping  Yi Shouxiang  Cao Xiangping
Affiliation:Department of Acupuncture & Massage, Hunan College of TCM, Changsha 410007, China.
Abstract:Hyperlipemia rabbit models established with high cholesterol and fat diet were treated with direct moxibustion and medicinal cake-separated moxibustion. The post-treatment plasma 6-keto-prostaglandin F1alpha (6-keto-PGF1alpha) and thromboxane B2 (TXB2) contents were determined by radioimmunoassay. Results indicated that the plasma 6-keto-PGF1alpha content significantly increased, the TXB2 level decreased (P < 0.05) and the TXB2 /6-keto-PGF1alpha ratio also decreased (P < 0.01) in the medicinal cake-separated moxibustion group as compared with those in the model group respectively, but there was no significant difference between the medicinal cake-separated moxibustion group and the direct moxibustion group (P > 0.05), suggesting that both the medicinal cake-separated moxibustion and direct moxibustion can regulate the plasma 6-keto-PGF1alpha and TXB2 contents, and the TXB2/6-keto-PGF1alpha ratio with similar actions, and have a certain protective action on endothelial cells of the aorta in the rabbit of hyperlipemia.
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