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国产及进口西罗莫司洗脱支架在糖尿病患者经皮冠状动脉介入治疗中应用效果的比较
引用本文:张菁,陈康寅.国产及进口西罗莫司洗脱支架在糖尿病患者经皮冠状动脉介入治疗中应用效果的比较[J].苏州大学学报(自然科学版),2008,28(6):999-1001,1023.
作者姓名:张菁  陈康寅
作者单位:张菁,ZHANG Jing(天津市第一中心医院,心内科,天津,300192);陈康寅,CHEN Kang-yin(天津医科大学第二附属医院,心内科,天津,300211) 
摘    要:目的 探讨应用国产及进口西罗莫司洗脱支架在糖尿病患者冠状动脉介入治疗中效果是否相似.方法 连续入选行冠状动脉介入治疗的糖尿病患者70例,应用Cypher(进口组;35例78个病变部位)或Firebird(国产组,35例66个病变部位)西罗莫司洗脱支架.术后6个月随访冠脉造影结果 及临床事件发生情况.结果 术后6个月,进口组患者晚期管腔丢失及支架内再狭窄百分比显著低于国产组,差异有高度统计学意义(P<0.01).但两组间临床不良事件(包括心源性死亡、急性心肌梗死、靶病变重建、靶血管重建)的差异均无统计学意义(P>0.05).两组患者在随访期间均未发生支架内血栓.结论 进口西罗莫司洗脱支架术后6个月时在造影结果 上具有一定的优势,但并没有体现在临床获益上,尚需进一步随访进行深入探讨.

关 键 词:国产  西罗莫司洗脱支架  糖尿病  经皮冠状动脉介入治疗

Comparable Outcomes of Domestic-made and Imported Sirolimus Eluting Stents in Diabetic Patients Undergoing Percutaneous Coronary Intervention
ZHANG Jing,CHEN Kang-yin.Comparable Outcomes of Domestic-made and Imported Sirolimus Eluting Stents in Diabetic Patients Undergoing Percutaneous Coronary Intervention[J].Suzhou University Journal of Medical Science,2008,28(6):999-1001,1023.
Authors:ZHANG Jing  CHEN Kang-yin
Institution:ZHANG Jing1,CHEN Kang-yin2(1.Dept of Cardiology,Tianjin First Central Hospital,Tianjin 300192,China,2.Dept of Cardiology,the Second Hospital Affiliated to Tianjin Medical University,Tianjin 300211,China)
Abstract:Objective To investigate whether the domestic-made and imported sirolimus eluting stents have similar efficacy in Chinese patients with diabetes.Methods A total of 70 diabetic patients who underwent percutaneous coronary intervention with Cypher(imported group;35 patients,78 lesions) or Firebird(domestic-made group;35 patients,66 lesions) stents were enrolled.Angiographic and clini-cal outcomes at 6 months were evaluated.Results On the 6th months,the imported group showed less late loss and restenosis perce...
Keywords:domestic-made  sirolimus eluting stents  diabetes  percutaneous coronary intervention outcome  
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