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Effect of Mifepristone on Transforming Growth Factor-β and its Receptor Transcription in Decidua, Villi and Serum Tumor Necrosis Factor -α Level in Early Human Gestation
作者姓名:Li-ping JIN1  Da-jin LI1  Jing-yu SHAO2  Song-guo ZHENG3  Xue-zhe WU21. Laboratory of Reproductive Immunology  Institute of Obstetrics and Gynecology  Fudan University  Shanghai 200011  China2. Shanghai First Maternity & Infant Health Hospital  Shanghai 200040  China3. Laboratory of Molecular Biology  Tumor Hospital  Fudan University  Shanghai 200032  China
作者单位:Li-ping JIN1,Da-jin LI1,Jing-yu SHAO2,Song-guo ZHENG3,Xue-zhe WU21. Laboratory of Reproductive Immunology,Institute of Obstetrics and Gynecology,Fudan University,Shanghai 200011,China2. Shanghai First Maternity & Infant Health Hospital,Shanghai 200040,China3. Laboratory of Molecular Biology,Tumor Hospital,Fudan University,Shanghai 200032,China
摘    要:Mifepristone is a progesterone antagonist which acts at the level of the receptor. Itbinds the progesterone receptor with a high affinity and antagonises progesterone biologicalaction. It has been applied in clinical use for multiple therapeutic purposes. In obstetrics andgynecology, mifepristone has been effective in medical termination of pregnancy in the firsttrimester. Mifepristone followed approximately 48 h later by a prostaglandin analog hasbeen reported to effect complete abortion in 9…

关 键 词:米非司酮 基因转换 生长发育 β-因子 受体 经期蜕膜 绒毛膜 免疫血清 坏疽 肿瘤 α-因子 早期妊娠 妊娠诊断
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