oxLDL,Lp（a）与脑血管疾病的关系

测定５１例脑血管病和２０例对照组的血浆ｏｘＬＤＬ和血清Ｌｐ（ａ）。结果脑血管病组明显高于对照组，脑血管病各分组（脑出血、脑栓塞、蛛网膜下腔出血）的ｏｘＬＤＬ亦高于对照组，脑出血、脑梗塞分组的Ｌｐ（ａ）高于对照组。ｏｘＬＤＬ及Ｌｐ（ａ）异常与患者的性别、年龄、病程及常规血脂检查异常率无相关。结论：ｏｘＬＰＬ、Ｌｐ（ａ）升高与脑血管病发病密切相关，是估价中风危险因素重要的、独立的脂蛋白参数之一。

Oxidized LDL and Lipoprotein(a) in patients with cerebrovascular disorders

We measured the oxidized LDL(oxLDL) of plasma and lipoprotein (a) Lp(a)] levels of serum on 51 patients with cerebrovascular dissorders and 20 cases of control group. A-mong 51 patients with cerebrovascular disorders,three groups of patients were included: patients with cerebral hemorrhage (CH), cerebral infarction (CD,and subarachnoid hemorrhage (SAH). The results revealed a significant difference on oxLDL levels in plasma between all patients groups and control group,either way on Lp(a). Morever.it showed the elevation of oxLDL and Lp(a) had no correlation with sex ,age,period of disease and the abnormal rate of routine blood lipid test. It was concluded that the elevation of oxLDL and Lp (a) is involved in the pathogenesis of cerebrovascular disorders. Lp(a) and oxLDL are important and independent lipoprotein parameters in evaluating the risk factors of cerebrovascular disorders.