| 脑缺血再灌注时红细胞免疫功能变化及中性粘多糖对其的影响 |
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| 引用本文： | 丁素菊,郑惠民.脑缺血再灌注时红细胞免疫功能变化及中性粘多糖对其的影响[J].中风与神经疾病杂志,1995,12(1):17-18. |
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| 作者姓名： | 丁素菊 郑惠民 |
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| 作者单位： | 上海第二军医大学长海医院神经内科
200433(丁素菊，郑惠民，郭峰)，上海第二军医大学长海医院神经内科 200433(侯晓军) |
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| 基金项目： | 上海市科委自然科学基金资助项目 |
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| 摘 要： | 本文采用脑缺血再灌注模型，观察沙土鼠红细胞免疫粘附（ＲＣＩＡ）功能变化，红细胞Ｃ３ｂ受体花环率（ＲＢＣ－Ｃ３ｂＲＲ）、红细胞免疫复合物花环率（ＲＢＣ－ＩＣＲ），和中性粘多糖（ＮＭ）对沙土鼠红细胞免疫功能的影响。结果表明：（１）缺血时ＲＢＣ－Ｃ３ｂＲＲ下降不明显（Ｐ〉０．０５），再灌注时明显下降（Ｐ〈０．００１）；（２）缺血和再灌注时ＲＢＣ－ＩＣＲ均升高（Ｐ〈０．００１）；３．提前用ＮＭ可提高再灌注
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| 关 键 词： | 脑缺血 再灌注 红细胞免疫 中性粘多糖 病理学 |
The changes of red cell immune function after cerebral ischemis and reperfusion in gerbil and effect of Neutral Mucopolysaccharide on it |
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| Ding Suju,Zheng Huimin,Gou Feng,et al..The changes of red cell immune function after cerebral ischemis and reperfusion in gerbil and effect of Neutral Mucopolysaccharide on it[J].Journal of Apoplexy and Nervous Diseases,1995,12(1):17-18. |
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| Authors: | Ding Suju Zheng Huimin Gou Feng |
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| Abstract: | The model of cerebral ischemia and reperfusion was performed in gerbil. We observed the changes of red cell immune functionjred blood cell C3brosette (RBC -C3bRR) .red blood cell immune coplex rosette (RBC - ICR), and Neutral Mu-copolysaccharide effecting on red cell immune. The results showed: 1- RBC -C3bRR didn't significantly decrease in ischemia (P>0. 05) , but markedly decreased in reperfusion (P< 0. 01,P<0. 001); 3. The pretreatmeant of NM can increase RBC-C3bRR,decrease RBC-ICR in reperfusion .The results indicated that cell immune function was effected by cerebral ischemia and reperfusion damage. NM can possess modulabili-ty red cell immune function . |
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| Keywords: | Reperfusion following cerebral ischemia RBC immune Neutral mucopoly saccharide |
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