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Transmission dynamics of pulmonary tuberculosis between autochthonous and immigrant sub-populations |
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| Authors: | Judit Barniol Stefan Niemann Valérie R Louis Bonita Brodhun Caroline Dreweck Elvira Richter Heiko Becher Walter Haas Thomas Junghanss |
| Affiliation: | (1) Section Clinical Tropical Medicine, Department for Infectious Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany;(2) Institute of Public Health, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany;(3) National Reference Centre for Mycobacteria, Research Centre Borstel, Parkallee 18, 23845 Borstel, Germany;(4) Department for Infectious Disease Epidemiology, Robert Koch Institute, DGZ-Ring 1, 13086 Berlin, Germany;(5) State Health Office Baden-W?rttemberg (Landesgesundheitsamt), Postfach 10 29 42, 70025, Stuttgart, Germany |
| Abstract: | BackgroundThe overall incidence of tuberculosis (TB) in Western Europe has been declining since the 19th Century. However, immigrant sub-groups from high-prevalence countries are slowing down this trend. The aim of this study was to describe how immigration influences TB transmission in Germany. For that we prospectively investigated the dynamics of TB transmission between TB high-prevalence immigrant and TB low-prevalence local populations with molecular epidemiological methods and conventional contact investigations. Besides, we assessed transmission in relation to social mixing using an innovative tool that measures the integration of immigrants into the local social environment. |
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