卵巢低反应获卵患者常规体外受精与卵胞浆单精子注射技术对妊娠结局的影响

目的比较卵巢低反应获卵患者常规体外受精与卵胞浆单精子注射技术对妊娠结局的影响。方法选择卵巢低反应获卵患者200例,将其分为两组,各100例。观察组采用卵胞浆单精子注射技术,对照组则实施常规体外受精技术,比较两组的移植结果及继续妊娠情况,并对着床患者随访1年,统计妊娠结局。结果观察组的受精率、可移植胚胎率、着床率、继续妊娠率均分别显著高于对照组（P〈0.05）;观察组的单胎妊娠率高于对照组,双胎妊娠、异位妊娠率低于对照组（P〈0.05）。结论对卵巢低反应获卵的不孕患者行卵胞浆单精子注射技术,相对于常规体外受精,具有更高的卵裂率和继续妊娠率,为卵巢低反应获卵的不孕患者采取何种受精方式提供了一个选择依据。

The influence of conventional in vitro fertilization and intracytoplasmic sperm injection technique on pregnancy outcome in patients with poor ovarian response of oocyte

Objective To compare the influence of conventional in vitro fertilization and intracytoplasmic sperm injection technique on pregnancy outcome in patients with poor ovarian response of oocyte. Methods 200 patients with poor ovarian response of oocyte were selected and divided into the two groups,and there were 100 cases in each group.The observation group was given intracytoplasmic sperm injection technique,the control group was given conventional in vitro fertilization technique,then transplant results and continue pregnancy situation and pregnancy outcome followed-up for 1 year in the two groups were compared. Results Fertilization rate,embryo transplantation rate,implantation rate and ongoing pregnancy rate in the observation group was significantly higher than that of the control group respectively（P〈0.05）;the pregnancy rate with single fetus in the observation group was higher than that in the control group,the twin pregnancy rate,ectopic pregnancy rate in the observation group was lower than that in the control group respectively（P〈0.05）. Conclusion Compared with the conventional in vitro fertilization,intracytoplasmic sperm injection technique conducted in infertility patients with poor ovarian response of oocyte has higher cleavage rate and ongoing pregnancy rate to provide the selected basis for patients with poor ovarian response of oocyte using what kind of fertilization method.