双源CT双能量肺灌注成像在诊断肺栓塞中的初步研究

目的探讨双源CT双能量扫描肺灌注成像（DEPI）和最小密度投影（MinP）的临床诊断价值。方法对临床疑肺动脉栓塞患者行双源CT双能量扫描,将扫描后数据传至工作站进行灌注成像分析;对肺组织灌注定量分析,进行统计学处理,同一患者的双侧比较行配对t检验,不同组别之间的比较行独立样本t检验;以融合数据的CTPA图像为标准,分别计算DEPI、MinP图像诊断肺栓塞的敏感度,特异度,阴性预测值,阳性预测值,比较采用配对卡方检验。结果灌注定量分析显示对照组双肺及双肺上、中、下部分别比较均无统计学意义（P〉0.05）;肺栓塞组灌注定量分析显示全肺及中、下肺比较均有统计学意义（P〈0.05）;DEPI和MinP图像与CTPA在诊断肺栓塞方面有较高的一致性。结论双源CT双能量扫描可用于肺栓塞的诊断,尤其有利于其早期发现和精确解剖定位。

The initial study on dual-energy lung perfusion imaging in the diagnosis of the pulmonary embolism using dual-source CT

Objective To explore the diagnostic values of dual energy lung perfusion and minimum intensity projection by dual-source CT（DSCT） .Methods Thirty patients who underwent dual energy scanning by DSCT were involved in this study.Thin-layer reconstruction of the data was transmitted to the workstation,quantitative analysis of lung tissue perfusion,paired t test and independent samples t test was applied respective-ly.CTPA images as the standard,the sensitivity,specificity,negative predictive value,positive predictive value of DEPI,MinP image diagnosing pulmonary embolism were calculated using paired chi-square test.Results Quantitative analysis of the control group showed that lung perfusion and lung upper,middle and bottom respectively,no statistically significant comparison（P〉 0.05） .The study group shows that the whole lung and the middle and lower lung comparison were statistically significant（P 〈0.05） .Conclusion pulmonary embolism can be analyzed by dual energy CT scanning,it is helpful to early discove and precisly anatomic locate the embolism.