小麦纤维素治疗儿童功能性便秘的疗效观察

目的：研究小麦纤维素治疗儿童功能性便秘的有效性和安全性。方法：采用前瞻性自身对照研究方法，对34例功能性便秘的患儿给予小麦纤维素治疗2周，观察治疗前后便秘症状及粪便性状改善情况，并进行量化评分比较。结果：治疗后3 d、7 d和14 d，粪便性状、排便间隔、排便困难积分均明显下降；便秘症状总积分也明显下降，与治疗前比较差异有统计学意义（P<0.05）。治疗后3、7、14 d总有效率分别为37%、87%和90%。医生非常满意和比较满意率为57%，患儿家长非常满意和比较满意率为63%。服用小麦纤维素期间无不良反应发生。结论：小麦纤维素治疗儿童功能性便秘疗效确切，安全性好。

Clinical trial of cellulose in treatment of functional constipation in children

Objective To study the efficacy and safety of cellulose for the treatment of functional constipation in children.Methods A prospective,self-controlled,clinical trial using cellulose was conducted for 2 weeks in 34 children with functional constipation.The constipation symptoms and the characteristics of feces after the treatment were observed.Results The characteristics of feces and the constipation symptoms were improved significantly after the treatment.The total efficacy rate was 37% 3 days after treatme...