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Avascular necrosis of bone in neuroblastoma treated with combination chemotherapy
Authors:Eiichi Ishii  Nobuyuki Yoshida  Sumio Miyazaki
Institution:(1) Department of Pediatrics, Faculty of Medicine, Kyushu University, Japan
Abstract:We treated two children with neuroblastoma and during the course of chemotherapy, avascular necrosis of the femoral head occurred. The main pathogenetic factor of this necrosis may be the toxic effect of cyclophosphamide.Abbreviations VMA vanillylmandelic acid - HVA homovanillic acid
Keywords:Avascular necrosis  Neuroblastoma  Cyclophosphamide
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