慢性乙肝湿热蕴脾证患者免疫球蛋白、补体水平的研究

对60例慢性乙肝湿热蕴脾证患者免疫球蛋白和补体的动态观察,发现慢乙肝湿热蕴脾证患者IgG高于正常值（P＜0.01）,IgA、IgM、C3、C4与正常值比较无显著差异;经中医辨证治疗后,IgG下降明显,治疗前后比较差异有显著性（P＜0.01）.提示慢性乙肝湿热蕴脾证患者HBV复制活跃,肝细胞炎症反应明显,体液免疫功能亢进;C3值正常说明湿热蕴脾证属邪正相持阶段,患者正气亏虚的程度不太严重.

Study on the Levels of Immune Globulin and Complement in Patients with Chronic Hepatitis B of Damp-heat Retention Spleen Syndrome

To observe the change of immune globulin and complement in 60 patients with chronic hepatitis B(CHB) of damp-heat retention spleen syndrome.The result showed that the level of IgG was higher than normal value(P<0.01),there were no obvious difference between IgA,IgM,C3,C4 and normal value.After treating with TCM differentiation,the level of IgG decreased markely,there was obvious difference before and after treatment(P<0.01).These patients showed active copy of HBV,obvious inflammation of liver cells and hyperfunction of humoral immunity.The C3 is normal,which indicates the patients are not too weak,and in the stage of healthy qi and pathological factor struggle.Treatment according to TCM differentiation can regulates the humoral immune function and improves the clinical symptom.