| 感冒软胶囊中葛根素的含量测定及其制剂分析 |
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| 引用本文： | 金迪,周爽,刘智宇,江蔚新,王金宏.感冒软胶囊中葛根素的含量测定及其制剂分析[J].黑龙江医药,2012,25(2):183-184. |
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| 作者姓名： | 金迪 周爽 刘智宇 江蔚新 王金宏 |
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| 作者单位： | 哈尔滨商业大学 |
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| 摘 要： | 目的:应用HPLC法测定感冒软胶囊中葛根素的含量。方法:采用高效液相色谱法;色谱柱:美国戴安公司C18柱(4.6mm×150mm,5μm);流动相:甲醇-水-0.1%醋酸(30:70),流速:1.0mL/min;检测波长:250nm;进样量:5μL。结果:葛根素在0.2-1.4μg范围内与峰面积呈良好线性关系,其回归方程为y=192235x+26939,r=0.9978;平均回收率为102.0%,RSD为1.82%(n=6)。结论:本法快速简便,准确,重现性好。
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| 关 键 词： | 高效液相 葛根素 感冒软胶囊 |
Determination of Puerarin in Cold Soft Capsules and Its Preparation Analysis |
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| Institution: | Jin Di,et al Harbin Commerce University(Harbin 150076) |
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| Abstract: | Objective:HPLC method for the determination of puerarin in a cold soft capsule content.Methods:using high performance liquid chromatography;column:Dionex Corporation U.S.C18 column(4.6mm × 150mm,5μm);mobile phase:methanol-water-0.1% acetic acid(30:70)flow rate:1.0mL /min;detection wavelength:250 nm;injection volume:5μL.Results:puerarin was within the range of 0.2-1.4μg good linear relationship between peak area,and the regression equation was y = 192235x + 26939,r = 0.9978;The average recovery was 102.0%,RSD was 1.82%(n = 6).Conclusion:This method is quick and easy,accurate and reproducible. |
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| Keywords: | HPLC puerarin cold soft capsules |
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