中西医结合治疗乙、丙型慢性活动性肝炎近期疗效观察

应用中药、微量元素制剂配合短疗程ａ－干扰素、促肝细胞生长因子治疗病毒性慢性活动性肝炎并肝硬化失代偿１８例（治疗组），并和１９例（对照组）随机对照，疗程３个月，结果：治疗组黄疸消失者占８８％（１６／１８），腹水消失９４％（１７／１８）；对照组分别为２６％（５／１９）和３７％（７／１９）。两组比较均Ｐ＜０．０１。ＡＬＴ、ＴＢｉｌ检验，治疗组均较对照组明显改善，均Ｐ＜０．０１，肝炎病毒复制标志物。ＨｂｓＡｇ、ＨｂｅＡｇ、抗－ＨｂｃｌｇＭ转阴率治疗组和对照组比，均有统计学差异意义。治疗组缓解率６８％（１２／１８），好转率２８％（５／１８），总有效率９４％（１７／１８）；对照组分别为１６％（３／１９），３６％（７／１９）和５２％（１０／１９）。两组比较，缓解率、总有效率差异均有统计学意义。

Observation of recent therapeutic effect of chronic active hepatitis B and C treated by TCM-WM

18 patients with chronic active hepatitis characterized by decompensated cirrhosis were treaded chinese medicine and microelement granule, a-interferon, PHGF as therapeutic group. Other 19 patients with same diseases were as control group only used expectant treatment. The curative course was for three. months. The results showed the elimination ratio of jaundice ascites were respectively were 88 %, 94N,but 26 % , 37 % in control group (P<0. 01 ) . ALT. TBil of therapeutic group were markedly provement than those of the control group (P<0. 01 ). Negative rate of HBsAg, anty-HBc IgM HBeAg of therapeutic group were higher than those of control group. The total effective rate was 94%,but 52% in control group. There was statistical meaning among two groups.