SPECT/CT同机融合显像对肿瘤患者骨转移灶的诊断价值

目的:评价SPECT/CT同机融合显像对单独SPECT难于确诊良恶性的骨病灶的鉴别诊断价值.方法:SPECT骨扫描难于确诊的对53例肿瘤患者的84个病灶行局部SPECT/CT同机融合断层显像.所有患者转移灶确诊以临床病理、MRI、CT、骨扫描复查或PET/CT检查为依据.结果:①SPECT显像无法确诊的84个病灶,经S...

SPECT/CT fusion Imaging for the diagnosis of metastatic bone lesions in cancer patients

Objective：To evaluate the SPECT/CT fusion imaging in the diagnosis of benign and malignant bone lesions classified as indeterminate on SPECT alone of cancer patients.Methods：Eighty four bone lesions of 53 cancer patients,for whom the natures of the lesions were not able to be determined by the 99Tcm-MDP whole-body bone scan,were examined by the SPECT/CT fusion imaging simultaneously.All of the images were blindly interpreted independently by 2 physicians.In cases of discrepancy,consensus was obtained by a second joint reading.The natures of the lesions were eventually confirmed by pathology or other imaging examination or follow-up diagnosis six months later.Results：①Of 84 equivocal bone lesions on bone SPECT,34（40.5%） could be correlated with osteolysis and/or sclerotic metastases findings and 44（52.4%） could be correlated with benign findings on SPECT/CT accurately.Even after analysis of the SPECT/CT images,5 lesions（6.0%） remained indeterminate and 1 lesion was misdiagnosed.②The diagnostic accuracy of SPECT/CT for the 84 bone lesions was 92.9%,and the sensitivity,specificity,positive prediction value and negative prediction value were 94.4%,91.7%,89.5% and 95.7% respectively.Conclusion：SPECT/CT fusion imaging can effectively increase the diagnostic accuracy of metastatic bone lesions in tumor patients.