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Breast cancer in young women (< or = 35 years): Genomic aberrations detected by comparative genomic hybridization |
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| Authors: | Weber-Mangal Susanne Sinn Hans-Peter Popp Susanne Klaes Rüdiger Emig Robert Bentz Martin Mansmann Ulrich Bastert Gunther Bartram Claus R Jauch Anna |
| Institution: | Institute of Human Genetics, University of Heidelberg, Germany. |
| Abstract: | Sporadic breast cancer in young women is different from the one in older patients regarding pathological features and aggressiveness of the tumors, but the spectrum of genetic alterations are largely unknown. We used comparative genomic hybridization (CGH) to analyze DNA copy number changes in 88 tumor samples from women |
| Keywords: | early onset breast cancer comparative genomic hybridization loss of 8p gain of 8q |
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