急性心肌梗死恢复期新发房颤的发生率与危险因素

目的 分析急性心肌梗死(AMI)患者恢复期（心肌梗死28 d后）出现新发房颤的发生率与危险因素。方法 回顾性分析2009年6月~2011年6月全部212例因AMI入住长征医院治疗且无房颤病史的患者一般情况，相关检查结果，以及心肌梗死1年内后续治疗、转归情况，并对可能影响患者恢复期新发房颤的因素进行logistic回归模型分析。结果 多因素logistic回归分析表明，高龄(P<0.05,OR=5.61)，高血压病（P<0.05，OR=5.89），左心室射血分数（LVEF）降低(P<0.01,OR=6.3)，未行急诊经皮冠状动脉介入（PCI）术（P<0.01，OR=6.01），糖尿病（P<0.05，OR=3.59）以及出院后无法耐受β受体阻滞剂治疗（P<0.01，OR=6.1）等是新发房颤的危险因素。结论 AMI患者恢复期出现新发房颤的危险因素为高龄，高血压病，LVEF降低，未行急诊PCI术，糖尿病以及出院后无法耐受β受体阻滞剂治疗。

Risk factors of new-onset atrial fibrillation during recovery period of acute myocardial infarction

AIM To explore the risk factors of new onset atrial fibrillation (AF) during the recovery period (>28 days) of acute myocardial infarction (AMI). METHODS Clinical data of 212 AMI patients during 1 year after admission were retrospectively analyzed, including the general conditions, test results, treatment and follow-up data. Patients were admitted to hospital for AMI from June 2009 to June 2011. Logistic regression analysis was conducted to analyze the risk factors of new-onset AF after hospital discharge. RESULTS Logistic regression analysis showed that age >75 years (P<0.05, OR=5.61), hypertension (P<0.05, OR=5.89), LVEF<50% (P<0.01, OR=6.3), non-emergency PCI (P<0.01, OR=6.01), diabetes mellitus (P<0.05, OR=3.59) and β-blocker intolerance (P<0.01, OR=6.1) were associated with an increased risk of new-onset AF during the recovery period of myocardial infarction. CONCLUSION Age >75 years, hypertension, LVEF<50%, non-emergency PCI, diabetes mellitus and β-blocker intolerance are risk factors for new-onset AF during the recovery period of AMI.