The origin of the genetic code and of the earliest oligopeptides |
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| Authors: | Edward N. Trifonov |
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| Affiliation: | aGenome Diversity Center, Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel;bDivision of Functional Genomics and Proteomics, Faculty of Science, Masaryk University, Kamenice 5, Brno CZ-62500, Czech Republic |
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| Abstract: | Reconstruction of the earliest proteins in the ancient binary alphabet [glycine family G, alanine family A] leads to repeats of G alternating with repeats of A. In addition, omnipresent motifs can be assembled in two of the earliest genes involved in energy supply, crucial for Life, i.e. ATP/GTP binding and ATPase activity. They are an almost perfect match to the alternating G and A and are complementary to each other. |
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| Keywords: | Early molecular evolution Origin of the genetic code Binary amino acid alphabet Coding in both strands |
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