ACI血小板、淋巴细胞膜Fas、APO2.7、bcl-2表达

测急性脑梗死（ＡＣＩ）患者血浆中血小板和淋巴细胞膜Ｆａｓ，ＡＰＯ．２７，ｂｃｌ－２阳性表达率，为研究上述促，抑凋亡基因对ＡＣＩ形成机制及预后的影响，寻找超早期防治措施。用流式细胞仪对制备好的血小板和淋巴细胞膜样本进行测定。结果：ＡＣＩ组血小板，Ｆａｓ，ＡＰＯ２．７ｂｃｌ－２阳性表达率均显著高于对照组，Ｐ〈０．０５。

ACI THROMBOCYTE AND LYMPHOCYTE MEMBRANE FAS APO2.7 bcl-2 EXPRESSION

To research promote or inhibit gene influence on the mechanism and prognosis of ACI, we measured hematoplasma thrombocyte and lymphocyte membrane FasAPO2.7, bcl 2 positive expression rate in the patients with acute cerebral ischemia (ACI). The samples of thrombocyte and lymphocyte were inspected with FCM. The results shew that Fas APO2.7 bcl 2 positive expression rate in the groups of patients with ACI was higher than the groups of normal group significantely, P <0.05. Lymphocyte membrane bcl 2 in the group of patients was lower singificantily than the group of control, the others were higher than group of control, P <0.01. These revealed the alterration that of Fas, APO2.7 and bcl 2 positive expression rate in thrombocyte and lymphocyte mabrane probably participated in the mechanism of ACI.