重症监护病房卒中相关性肺炎的危险因素分析

目的分析重症监护病房（ICU）急性脑卒中患者伴发卒中相关性肺炎（SAP）的危险因素。方法对南京医科大学第一附属医院2010年3月1日至2011年3月31日人住ICU的101例急性脑卒中患者的临床资料进行回顾性分析。结果101例急性脑卒中患者中发生SAP共30例（29．70％）。单因素分析显示：SAP组与非SAP组在年龄、糖尿病既往史、脑卒中既往史、卒中后吞咽困难、机械通气、气管切开及住院天数等方面的差异具有统计学意义（P〈O．05）。Logistic回归分析显示，男性、糖尿病既往史、卒中后吞咽困难及气管切开是本地区患者SAP的独立危险因素。结论ICU中SAP危险因素是多方面的，应重视其防治。影响疾病发生发展的其他危险因素尚需进一步探讨。

Risk factors for stroke-associated pneumonia in intensive care unit

Objective To analyze the risk factors for stroke-associated pneumonia （SAP） in intensive care unit （ICU）. Methods We retrospectively studied the clinical data of 101 patients with acute stroke who were admitted to ICU of First Affiliated Hospital of Nanjing Medical University between 1 March 2010 and 31 March 2011. Results Thirty out of 101 patients developed SAP （29.70%）. One-way analysis of variance showed that differences of age, diabetes history, stroke history, dysphagia after stroke, mechanical ventilation, tracheotomy and length of stay between SAP and non-SAP group were significant （P 〈 0.05）. According to the logistic regression model, male gender, diabetes history, dysphagia after stroke and tracheotomy were independent risk factors for SAP in east China. Conclusion The prevalence of SAP in acute stroke patients admitted to ICU was associated with multiple factors and prevention of SAP in acute stroke patients should be warranted. Other potential risk factors of SAP need to be evaluated in further studies.