| 姜黄素抗肿瘤药理作用的研究进展 |
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| 引用本文： | 崔明花,付二花,林贞花,朴英实. 姜黄素抗肿瘤药理作用的研究进展[J]. 中国临床药理学杂志, 2021, 0(2): 186-188,196 |
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| 作者姓名： | 崔明花 付二花 林贞花 朴英实 |
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| 作者单位： | 延边大学医学院 |
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| 基金项目： | 吉林省卫生与健康青年科技骨干培养计划项目(2018Q039)。 |
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| 摘 要： | 姜黄素是从姜科、天南星科等植物的根茎中提取的一种酸性多酚化合物,具有良好的抗炎及抗肿瘤作用.本文针对姜黄素对肿瘤的增殖、侵袭与转移、细胞能量代谢、血管生成、凋亡、自噬、免疫调节、逆转多药耐药性等方面的抗肿瘤药理作用及分子机制做一综述.
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| 关 键 词： | 姜黄素 肿瘤 分子机制 |
Research progress of pharmacological functions on tumor suppression by curcumin |
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| CUI Ming-hua,FU Er-hua,LIN Zhen-hua,PIAO Ying-shi. Research progress of pharmacological functions on tumor suppression by curcumin[J]. The Chinese Journal of Clinical Pharmacology, 2021, 0(2): 186-188,196 |
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| Authors: | CUI Ming-hua FU Er-hua LIN Zhen-hua PIAO Ying-shi |
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| Affiliation: | (Medical College,Yanbian University,Yanji 133002,Jilin Province,China) |
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| Abstract: | Curcumin is an acidic polyphenolic compound extracted from rhizomes of plants such as Turmeric and Araceae,which has a good anti-tumor effect.In this paper,the effects of curcumin on tumor proliferation,invasion and metastasis,cell energy metabolism,angiogenesis,apoptosis,autophagy,immune regulation,reversal of multidrug resistance and their molecular mechanisms were reviewed. |
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| Keywords: | curcumin anti-tumor molecular mechanisms |
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