番茄红素对SD老龄大鼠抗氧化作用的影响

目的:探讨番茄红素对SD老龄大鼠抗氧化作用的影响.方法:48只SD老龄大鼠以初始血清中丙二醛(MDA)的含量随机分成3个实验组和1个对照组.各组大鼠分别经口灌胃给予0.066 4 g/(kg·天)、0.134 0g/(kg·天)、0.400 0 g/(kg·天)的番茄红素及食用油30天后,测定血清中MDA含量、超氧化物歧化酶(SOD)活力、谷胱甘肽过氧化物酶(GSH-Px)活力、肝组织中脂褐质含量.结果:0.4 g/(kg·天)组大鼠血清中MDA含量显著低于对照组,0.134 g/(kg·天)、0.400 g/(kg·天)组大鼠血清中SOD活力显著高于对照组.结论:番茄红素对SD老龄大鼠具有抗氧化作用.

Effect of lycopene on antioxidation in SD old rats

Objective:To study the effects of the lycopene on antioxidation in SD old rats. Methods:According to the initial contents of malondiadehycle(MDA) in the serum, 48 SD old rats were devided radomly to 4 groups. After the rats were orally administered with 0.066 4 g/(kg·d), 0.134 g/(kg·d), 0.4 g/(kg·d) lycopene and the oil for 30 days, the concents of serum MDA, the energy of serum SA, the energy of serum GSH-Px and the contents of lipofasciin in liver were observed. Results:Compared with the oil group, the concents of serum MDA were decreased significantly in 0.4 g/(kg·d) group, and the energy of serum SA was increased significantly in 0.134 g/(kg·d) and 0.4 g/(kg·d) groups. Conclusion:Lycopene has antioxidant effect on SD old rats.