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GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study
Authors:Aleksandra A. Szwedo MS  Ingvild Dalen PhD  Kenn Freddy Pedersen MD  PhD  Marta Camacho MS  David Bäckström MD  PhD  Lars Forsgren MD  PhD  Charalampos Tzoulis MD  PhD  Sophie Winder-Rhodes PhD  Gavin Hudson PhD  Ganqiang Liu PhD  Clemens R. Scherzer MD  Rachael A. Lawson PhD  Alison J. Yarnall FRCP  PhD  Caroline H. Williams-Gray MRCP  PhD  Angus D. Macleod MRCP  PhD  Carl E. Counsell MRCP  MD  Ole-Bjørn Tysnes MD  PhD  Guido Alves MD  PhD  Jodi Maple-Grødem PhD  Parkinson's Incidence Cohorts Collaboration
Affiliation:1. The Norwegian Center for Movement Disorders, Stavanger University Hospital, Stavanger, Norway

Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway;2. Department of Research, Section of Biostatistics, Stavanger University Hospital, Stavanger, Norway;3. The Norwegian Center for Movement Disorders, Stavanger University Hospital, Stavanger, Norway

Department of Neurology, Stavanger University Hospital, Stavanger, Norway;4. Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK;5. Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden

Department of Neurology, and Department of Neuroscience, Yale University School of Medicine, New Haven, Connecticut, USA;6. Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden;7. Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway

Department of Clinical Medicine, University of Bergen, Bergen, Norway;8. Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK

Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, UK;9. Neurobiology Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong, China;10. Center for Advanced Parkinson Research, Harvard Medical School, Brigham and Women's Hospital, Boston, USA;11. Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK;12. Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK;13. The Norwegian Center for Movement Disorders, Stavanger University Hospital, Stavanger, Norway

Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway

Department of Neurology, Stavanger University Hospital, Stavanger, Norway;14. The Norwegian Center for Movement Disorders, Stavanger University Hospital, Stavanger, Norway

Abstract:
Keywords:Parkinson's disease  dementia  cognitive decline  APOE  GBA
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