正常脑脊液流动的磁共振定性研究

目的探讨MRI 相位对比电影序列 （cine PC） 定性分析脑脊液流动的可能性,并运用该技术对正常志愿者进行分析.方法采用MRI cine PC序列对15名正常志愿者的脑室、脑池和颈椎管内蛛网膜下腔的脑脊液流动进行定性观察,并对心脏周期不同时段脑脊液流动方向的变化进行分析.结果 MRI cine PC序列可清楚地显示心脏周期各个时段各个脑室、脑池和脊髓蛛网膜下腔中脑脊液运动方向的变化.结论 MRI cine PC法是一种新型的无创性的检查手段,对脑脊液的流动有很强的敏感性,是一种很有前途的研究手段.

MRI qualitative estimation of cerebrospinal fluid flow in normal volunteers

Objective To evaluate the feasibility of the cerebrospinal fluid (CSF) flow measurement by cine phase contrast MRI. Methods Evaluation of intracranial and intraspinal CSF flow was accomplished by the use of periphery gated cine phase contrast MRI technique. Normal patterns of pulsatile flow within the ventricles, cisterns and cervical subarachnoid space were established by this technique. Results CSF flow within ventricle, cistern and subarachnoid space could be clearly displayed, and the relationships between the cardiac cycle and the CSF pulsations were demonstrated on both magnitude reconstruction and phase reconstruction MR images. Conclusions Cine phase contrast MRI is capable of demonstrating intracranial and intraspinal CSF flow. As a new noninvasive technique, it is really superior than other modalities in studying the flow pattern and direction of CSF.