玻璃体切除和自体血小板治疗特发性黄斑裂孔

目的评价玻璃体切除、浓缩自体血小板和气体眼内填充治疗全层特发性黄斑裂孔的效果。方法对6例全层特发性黄斑裂孔患者的6只眼采用玻璃体切除，剥除玻璃体后皮质，气液交换，自体血小板溶液滴于后极部，20%～30%SF6注入玻璃体腔的方法进行治疗。术后患者仰卧1小时，然后俯卧2周。结果手术后9天～12个月6只眼黄斑裂孔闭合，视网膜平复。视力改善2行以上5只眼，占83.3%，视力达到0.3以上者4只眼，占66.7%，1只眼发生周边视网膜新裂孔伴视网膜脱离。结论玻璃体切除、浓缩自体血小板和气体眼内填充可使全层特发性黄斑裂孔闭合，视力提高。(中华眼底病杂志,1998,14:14-15)

Vitrectomy and autologous platelet concentrate for the treatment of idiopathic macular holes

PurposeTo assess the efficacy of pars plana vitrectomy,autologous platelet concentrate and gas tamponade for the treatment of full-thickness idiopathic macular holes.MethodsThe procedures consisted of pars plana vitrectomy with removal of posterior cortical vitreous，air-fluid exchange, instillation of autologous platelet concentrate onto the posterior pole and 20%～30%SF6 tamponade,were performed in treating 6 eyes of 6 patients with idiopathic macular holes. The patients were instructed to lie in a supine position for l hour after surgery,then adviced to remain in a facedown position for 2 weeks.ResultsFlattening of the surrounding retina and closure of the hole were achieved postoperatively in all the 6 affected eyes.Visual acuity improved two lines or more in 5 eyes (83.3%).Four eyes(66.7%)reached a postoperative visual acuity of 0.3 or more. Retinal detachment ocurred in one eye owing to peripheral new hole formation.ConclusionPars plana vitrectomy, autologous platelet concentrate and gas tamponade for the treatment of full-thickness idiopathic macular holes are able to close macular hole and improve the visual acuity.(Chin J Ocul Fundus Dis,1998,14:14-15)