吲哚-3-乙酸对人外周血淋巴细胞微核和SCE频率的影响 |
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引用本文: | 胡晓岩,黄辰,宋土生,王艾英. 吲哚-3-乙酸对人外周血淋巴细胞微核和SCE频率的影响[J]. 癌变.畸变.突变, 2004, 16(3): 171-172 |
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作者姓名: | 胡晓岩 黄辰 宋土生 王艾英 |
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作者单位: | 西安交通大学医学院遗传教研室,陕西,西安,710061 |
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摘 要: | 背景与目的:研究吲哚-3-乙酸对人体外周血淋巴细胞微核和SCE频率的影响.材料与方法:应用人体外周血淋巴细胞测定吲哚-3-乙酸诱导微核形成率试验和姊妹染色单体互换率(SCE).结果:各吲哚-3-乙酸处理组与阴性对照组相比,微核形成率和SCE差异均存在显著性.结论:吲哚-3-乙酸对人外周血淋巴细胞的遗传物质具有损伤作用.
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关 键 词: | 吲哚-3-乙酸 姊妹染色单体互换(SCE) 微核 |
文章编号: | 1004-616(2004)03-0171-02 |
修稿时间: | 2003-06-23 |
The Effect of the Indole-3-Acetic Acid on the SCE and Micronuclei of Hunan Peripheral Lymphocytes |
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Abstract: | BACKGROUND&AIM: To study the effect of the indole-3-acetic acid(IAA)on the SCE and micronuclei of human peripheral lymphocytes. MATERIAL AND METHODS: We apply IAA to detect micronuclei and SCE of human peripheral lymphocytes. RESULTS: There were salience difference on the micronuclei rate and SCE rate between each group treated with different concentration of the indole-3-acetic acid and the negative controlled group(P<0.05) .CONCLUSION: The indole-3-acetic acid damaged the genetic material of human peripheral lymphocytes. |
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Keywords: | Indole-3-acetic acid SCE micronuclei |
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