| 吲哚-3-乙酸对人外周血淋巴细胞微核和SCE频率的影响 |
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| 引用本文： | 胡晓岩,黄辰,宋土生,王艾英.吲哚-3-乙酸对人外周血淋巴细胞微核和SCE频率的影响[J].癌变．畸变．突变,2004,16(3):171-172. |
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| 作者姓名： | 胡晓岩 黄辰 宋土生 王艾英 |
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| 作者单位： | 西安交通大学医学院遗传教研室,陕西,西安,710061 |
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| 摘 要： | 背景与目的:研究吲哚-3-乙酸对人体外周血淋巴细胞微核和SCE频率的影响.材料与方法:应用人体外周血淋巴细胞测定吲哚-3-乙酸诱导微核形成率试验和姊妹染色单体互换率(SCE).结果:各吲哚-3-乙酸处理组与阴性对照组相比,微核形成率和SCE差异均存在显著性.结论:吲哚-3-乙酸对人外周血淋巴细胞的遗传物质具有损伤作用.
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| 关 键 词： | 吲哚-3-乙酸 姊妹染色单体互换(SCE) 微核 |
| 文章编号： | 1004-616(2004)03-0171-02 |
| 修稿时间： | 2003年6月23日 |
The Effect of the Indole-3-Acetic Acid on the SCE and Micronuclei of Hunan Peripheral Lymphocytes |
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| Abstract: | BACKGROUND&AIM: To study the effect of the indole-3-acetic acid(IAA)on the SCE and micronuclei of human peripheral lymphocytes. MATERIAL AND METHODS: We apply IAA to detect micronuclei and SCE of human peripheral lymphocytes. RESULTS: There were salience difference on the micronuclei rate and SCE rate between each group treated with different concentration of the indole-3-acetic acid and the negative controlled group(P<0.05) .CONCLUSION: The indole-3-acetic acid damaged the genetic material of human peripheral lymphocytes. |
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| Keywords: | Indole-3-acetic acid SCE micronuclei |
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