| 理气颗粒的质量标准研究 |
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| 引用本文： | 张锦林,季屹红,卫小瑾,倪美鑫. 理气颗粒的质量标准研究[J]. 西部中医药, 2017, 30(9). DOI: 10.3969/j.issn.1004-6852.2017.09.014 |
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| 作者姓名： | 张锦林 季屹红 卫小瑾 倪美鑫 |
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| 作者单位： | 南通大学附属肿瘤医院药学部,江苏 南通,226361 |
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| 基金项目： | 南通市青年医学人才科研基金项目 |
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| 摘 要： | 目的:建立理气颗粒的质量标准。方法:采用薄层色谱法对制剂中的丹参、当归和大黄进行薄层鉴别,采用高效液相色谱法对理气颗粒中丹酚酸B进行含量测定。结果:薄层色谱斑点清晰,阴性对照无干扰;丹酚酸B在17.80~106.8μg/m L之间线性关系良好(r=0.999 6),精密度、稳定性、重复性试验的RSD2%,平均回收率为97.31%(RSD=2.627%)。结论:该方法稳定、简单、准确,可作为理气颗粒的质量控制标准。
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| 关 键 词： | 理气颗粒 薄层色谱法 高效液相色谱法 质量标准 |
Research on Quality Standard of LiQi Granules |
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| ZHANG Jinlin,JI Yihong,WEI Xiaojin,NI Meixin. Research on Quality Standard of LiQi Granules[J]. Western Journal of Traditional Chinese Medicine, 2017, 30(9). DOI: 10.3969/j.issn.1004-6852.2017.09.014 |
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| Authors: | ZHANG Jinlin JI Yihong WEI Xiaojin NI Meixin |
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| Abstract: | Objective: To establish the quality standard for LiQi granules. Methods: DanShen (salvia miltiorrhiza), DangGui(Angelica sinensis) and DaHuang(rheum officinale) in the preparations were identified by using TCL, the contents of Salvianolic Acid B in LiQi granules were detected by adopting HPLC. Results:The spots of TLC were clear and no interference was found in the negative control; Salvianolic Acid B showed better linear relationship in the range between 17.80 and 106.80 μg/mL(r=0.9996), RSDs of precision, stability and repeatability were less than 2%, mean average recovery was 97.31%(RSD=2.627%). Conclusion:The method, stable, simple and accurate, could be used as the standard of quality standard for LiQi granules. |
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| Keywords: | LiQi granules TLC HPLC quality standard |
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