Drug concentrations in axillary lymph nodes after lymphatic chemotherapy on patients with breast cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Drug concentrations in axillary lymph nodes after lymphatic chemotherapy on patients with breast cancer

Authors:	Jianghao?Chen author-information" > author-information__contact u-icon-before" > mailto:chenjh@fmmu.edu.cn" title=" chenjh@fmmu.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Ling?Wang,Qing?Yao,Rui?Ling,Kaizong?Li,Hui?Wang

Affiliation:	(1) Department of Vascular and Endocrine Surgery, First Affiliated Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China;(2) Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China

Abstract:	Background Lymph node status is one of the decisive prognostic factors in breast cancer. Chemotherapy targeting regional lymphatic tissues has emerged as a promising therapy for the treatment of malignancies with a high tendency to disseminate lymphatically. The present study determined the drug concentrations in axillary lymph nodes after lymphatic chemotherapy (LC) in patients with breast cancer and compared the results with those receiving intravenous chemotherapy (VC) to investigate whether LC could improve the accumulation of anticancer drug in regional lymph nodes.

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