铜绿假单胞菌医院感染分布及耐药性分析

目的 了解医院铜绿假单胞菌感染分布及对20种抗菌药物的耐药性,为医院监测控制及合理选用抗菌药物提供依据.方法 对2008年1月-2009年12月分离的156株铜绿假单胞菌药敏结果进行同顾分析,并记录其感染部位、标本分布及药敏试验.结果 铜绿假单胞菌对三代头孢菌素有较高的耐药性,156株铜绿假单胞菌对阿米卡星敏感率最高为90.4％,其他是亚胺培南为87.2％、氨曲南为69.2％等.结论 铜绿假单胞菌感染以呼吸道为主,可引起多部位感染,其对常用抗菌药物具有较高的耐药性,应引起临床与实验人员的重视,临床用药应以药敏试验结果为指导,合理使用抗菌药物.

Distribution of Pseudomonas aeruginosainfections and analysis of drug resistance

OBJECTIVE To understand the distribution of Pseudomonas aeruginosa infection and its drug resistance to 20 antibiotics,to provide bases for the monitoring,control and rational use of antibiotics in hospital.METHODS From Jan 2008 to Dec 2009,a total of 156 strains of P.aeruginosa were isolated,the result of the drug susceptibility testing was retrospectively analyzed,the infection sites,distribution of the specimens,and drug susceptibility testing were recorded.RESULTS The drug susceptibility testing indicated that P.aeruginosa was highly resistant to the third generation cephalosporins,the susceptibility rate of 156 P.aeruginosa strains to amikacin was the highest(90.38%),followed by imipenem(87.2%) and aztreonam(69.2%).CONCLUSION P.aeruginosa infection mainly occurs in respiratory tract,P.aeruginosa can cause infections in multiple sites;its drug resistance to common antibiotics is high,so the clinicians should attach great importance to the rational use of antibiotics on the basis of drug susceptibility testing.